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Functional Role and Affinity of Inorganic Cations in Stabilizing the Tetrameric Structure of the KcsA K(+) Channel
Crystal structures of the tetrameric KcsA K(+) channel reveal seven distinct binding sites for K(+) ions within the central pore formed at the fourfold rotational symmetry axis. Coordination of an individual K(+) ion by eight protein oxygen atoms within the selectivity filter suggests that ion-subun...
Autores principales: | Krishnan, Manoj N., Bingham, Jon-Paul, Lee, Siew Hwee, Trombley, Patrick, Moczydlowski, Edward |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266582/ https://www.ncbi.nlm.nih.gov/pubmed/16129774 http://dx.doi.org/10.1085/jgp.200509323 |
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