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Long Polyamines Act as Cofactors in PIP(2) Activation of Inward Rectifier Potassium (Kir2.1) Channels

Phosphatidylinosital-4,5-bisphosphate (PIP(2)) acts as an essential factor regulating the activity of all Kir channels. In most Kir members, the dependence on PIP(2) is modulated by other factors, such as protein kinases (in Kir1), G(βγ) (in Kir3), and the sulfonylurea receptor (in Kir6). So far, ho...

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Detalles Bibliográficos
Autores principales: Xie, Lai-Hua, John, Scott A., Ribalet, Bernard, Weiss, James N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266595/
https://www.ncbi.nlm.nih.gov/pubmed/16316973
http://dx.doi.org/10.1085/jgp.200509380