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Separate Ion Pathways in a Cl(−)/H(+) Exchanger
CLC-ec1 is a prokaryotic CLC-type Cl(−)/H(+) exchange transporter. Little is known about the mechanism of H(+) coupling to Cl(−). A critical glutamate residue, E148, was previously shown to be required for Cl(−)/H(+) exchange by mediating proton transfer between the protein and the extracellular sol...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266597/ https://www.ncbi.nlm.nih.gov/pubmed/16316975 http://dx.doi.org/10.1085/jgp.200509417 |