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Calcium Activation of Ryanodine Receptor Channels—Reconciling RyR Gating Models with Tetrameric Channel Structure

Despite its importance and abundance of experimental data, the molecular mechanism of RyR2 activation by calcium is poorly understood. Recent experimental studies involving coexpression of wild-type (WT) RyR2 together with a RyR2 mutant deficient in calcium-dependent activation (Li, P., and S.R. Che...

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Detalles Bibliográficos
Autores principales: Zahradník, Ivan, Györke, Sándor, Zahradníková, Alexandra
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266604/
https://www.ncbi.nlm.nih.gov/pubmed/16260840
http://dx.doi.org/10.1085/jgp.200509328