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Charge Screening by Internal pH and Polyvalent Cations as a Mechanism for Activation, Inhibition, and Rundown of TRPM7/MIC Channels

The Mg(2+)-inhibited cation (MIC) current, believed to represent activity of TRPM7 channels, is found in lymphocytes and mast cells, cardiac and smooth muscle, and several other eukaryotic cell types. MIC current is activated during whole-cell dialysis with divalent-free internal solutions. Millimol...

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Detalles Bibliográficos
Autores principales: Kozak, J. Ashot, Matsushita, Masayuki, Nairn, Angus C., Cahalan, Michael D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266608/
https://www.ncbi.nlm.nih.gov/pubmed/16260839
http://dx.doi.org/10.1085/jgp.200509324