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Charge Screening by Internal pH and Polyvalent Cations as a Mechanism for Activation, Inhibition, and Rundown of TRPM7/MIC Channels
The Mg(2+)-inhibited cation (MIC) current, believed to represent activity of TRPM7 channels, is found in lymphocytes and mast cells, cardiac and smooth muscle, and several other eukaryotic cell types. MIC current is activated during whole-cell dialysis with divalent-free internal solutions. Millimol...
Autores principales: | Kozak, J. Ashot, Matsushita, Masayuki, Nairn, Angus C., Cahalan, Michael D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266608/ https://www.ncbi.nlm.nih.gov/pubmed/16260839 http://dx.doi.org/10.1085/jgp.200509324 |
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