Functionally Active T1-T1 Interfaces Revealed by the Accessibility of Intracellular Thiolate Groups in Kv4 Channels

Gating of voltage-dependent K(+) channels involves movements of membrane-spanning regions that control the opening of the pore. Much less is known, however, about the contributions of large intracellular channel domains to the conformational changes that underlie gating. Here, we investigated the fu...

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Detalles Bibliográficos
Autores principales: Wang, Guangyu, Shahidullah, Mohammad, Rocha, Carmen A., Strang, Candace, Pfaffinger, Paul J., Covarrubias, Manuel
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266617/
https://www.ncbi.nlm.nih.gov/pubmed/15955876
http://dx.doi.org/10.1085/jgp.200509288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266617/
https://www.ncbi.nlm.nih.gov/pubmed/15955876
http://dx.doi.org/10.1085/jgp.200509288

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