Pharmacological Properties and Functional Role of K(slow) Current in Mouse Pancreatic β-Cells: SK Channels Contribute to K(slow) Tail Current and Modulate Insulin Secretion

The pharmacological properties of slow Ca(2+)-activated K(+) current (K(slow)) were investigated in mouse pancreatic β-cells and islets to understand how K(slow) contributes to the control of islet bursting, [Ca(2+)](i) oscillations, and insulin secretion. K(slow) was insensitive to apamin or the K(...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Houamed, Khaled, Kupershmidt, Sabina, Roden, Dan, Satin, Leslie S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266621/
https://www.ncbi.nlm.nih.gov/pubmed/16186562
http://dx.doi.org/10.1085/jgp.200509312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266621/
https://www.ncbi.nlm.nih.gov/pubmed/16186562
http://dx.doi.org/10.1085/jgp.200509312

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