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Gating and Ionic Currents Reveal How the BK(Ca) Channel's Ca(2+) Sensitivity Is Enhanced by its β1 Subunit

Large-conductance Ca(2+)-activated K(+) channels (BK(Ca) channels) are regulated by the tissue-specific expression of auxiliary β subunits. β1 is predominately expressed in smooth muscle, where it greatly enhances the BK(Ca) channel's Ca(2+) sensitivity, an effect that is required for proper re...

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Detalles Bibliográficos
Autores principales: Bao, Lin, Cox, Daniel H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266624/
https://www.ncbi.nlm.nih.gov/pubmed/16186565
http://dx.doi.org/10.1085/jgp.200509346