EndoS from Streptococcus pyogenes is hydrolyzed by the cysteine proteinase SpeB and requires glutamic acid 235 and tryptophans for IgG glycan-hydrolyzing activity

BACKGROUND: The endoglycosidase EndoS and the cysteine proteinase SpeB from the human pathogen Streptococcus pyogenes are functionally related in that they both hydrolyze IgG leading to impairment of opsonizing antibodies and thus enhance bacterial survival in human blood. In this study, we further...

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Detalles Bibliográficos
Autores principales: Allhorn, Maria, Olsén, Arne, Collin, Mattias
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266755/
https://www.ncbi.nlm.nih.gov/pubmed/18182097
http://dx.doi.org/10.1186/1471-2180-8-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266755/
https://www.ncbi.nlm.nih.gov/pubmed/18182097
http://dx.doi.org/10.1186/1471-2180-8-3

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