Integrative Genome-Wide Expression Analysis Bears Evidence of Estrogen Receptor-Independent Transcription in Heregulin-Stimulated MCF-7 Cells

Heregulin ß-1 (HRG) is an extracellular ligand that activates mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-OH kinase (PI3K)/Akt signaling pathways through ErbB receptors. MAPK and Akt have been shown to phosphorylate the estrogen receptor (ER) at Ser-118 and Ser-167, respective...

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Detalles Bibliográficos
Autores principales: Nagashima, Takeshi, Suzuki, Takahiro, Kondo, Shinji, Kuroki, Yoko, Takahashi, Kaoru, Ide, Kaori, Yumoto, Noriko, Hasegawa, Aki, Toyoda, Tetsuro, Kojima, Toshio, Konagaya, Akihiko, Suzuki, Harukazu, Hayashizaki, Yoshihide, Sakaki, Yoshiyuki, Hatakeyama, Mariko
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266794/
https://www.ncbi.nlm.nih.gov/pubmed/18350142
http://dx.doi.org/10.1371/journal.pone.0001803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266794/
https://www.ncbi.nlm.nih.gov/pubmed/18350142
http://dx.doi.org/10.1371/journal.pone.0001803

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