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Identification of Direct Target Genes Using Joint Sequence and Expression Likelihood with Application to DAF-16

A major challenge in the post-genome era is to reconstruct regulatory networks from the biological knowledge accumulated up to date. The development of tools for identifying direct target genes of transcription factors (TFs) is critical to this endeavor. Given a set of microarray experiments, a prob...

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Detalles Bibliográficos
Autores principales: Yu, Ron X., Liu, Jie, True, Nick, Wang, Wei
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266795/
https://www.ncbi.nlm.nih.gov/pubmed/18350157
http://dx.doi.org/10.1371/journal.pone.0001821