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Identification of Direct Target Genes Using Joint Sequence and Expression Likelihood with Application to DAF-16
A major challenge in the post-genome era is to reconstruct regulatory networks from the biological knowledge accumulated up to date. The development of tools for identifying direct target genes of transcription factors (TFs) is critical to this endeavor. Given a set of microarray experiments, a prob...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266795/ https://www.ncbi.nlm.nih.gov/pubmed/18350157 http://dx.doi.org/10.1371/journal.pone.0001821 |