Improving Phrap-Based Assembly of the Rat Using “Reliable” Overlaps

The assembly methods used for whole-genome shotgun (WGS) data have a major impact on the quality of resulting draft genomes. We present a novel algorithm to generate a set of “reliable” overlaps based on identifying repeat k-mers. To demonstrate the benefits of using reliable overlaps, we have creat...

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Detalles Bibliográficos
Autores principales: Roberts, Michael, Zimin, Aleksey V., Hayes, Wayne, Hunt, Brian R., Ustun, Cevat, White, James R., Havlak, Paul, Yorke, James
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266800/
https://www.ncbi.nlm.nih.gov/pubmed/18350171
http://dx.doi.org/10.1371/journal.pone.0001836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266800/
https://www.ncbi.nlm.nih.gov/pubmed/18350171
http://dx.doi.org/10.1371/journal.pone.0001836

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