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Improving Phrap-Based Assembly of the Rat Using “Reliable” Overlaps
The assembly methods used for whole-genome shotgun (WGS) data have a major impact on the quality of resulting draft genomes. We present a novel algorithm to generate a set of “reliable” overlaps based on identifying repeat k-mers. To demonstrate the benefits of using reliable overlaps, we have creat...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266800/ https://www.ncbi.nlm.nih.gov/pubmed/18350171 http://dx.doi.org/10.1371/journal.pone.0001836 |