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Statistical Modeling of Transcription Factor Binding Affinities Predicts Regulatory Interactions

Recent experimental and theoretical efforts have highlighted the fact that binding of transcription factors to DNA can be more accurately described by continuous measures of their binding affinities, rather than a discrete description in terms of binding sites. While the binding affinities can be pr...

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Detalles Bibliográficos
Autores principales: Manke, Thomas, Roider, Helge G., Vingron, Martin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266803/
https://www.ncbi.nlm.nih.gov/pubmed/18369429
http://dx.doi.org/10.1371/journal.pcbi.1000039