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Electrotonic Signals along Intracellular Membranes May Interconnect Dendritic Spines and Nucleus

Synapses on dendritic spines of pyramidal neurons show a remarkable ability to induce phosphorylation of transcription factors at the nuclear level with a short latency, incompatible with a diffusion process from the dendritic spines to the nucleus. To account for these findings, we formulated a nov...

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Detalles Bibliográficos
Autores principales: Shemer, Isaac, Brinne, Björn, Tegnér, Jesper, Grillner, Sten
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266990/
https://www.ncbi.nlm.nih.gov/pubmed/18369427
http://dx.doi.org/10.1371/journal.pcbi.1000036