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An Integrative Genomic and Epigenomic Approach for the Study of Transcriptional Regulation
The molecular heterogeneity of acute leukemias and other tumors constitutes a major obstacle towards understanding disease pathogenesis and developing new targeted-therapies. Aberrant gene regulation is a hallmark of cancer and plays a central role in determining tumor phenotype. We predicted that i...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266992/ https://www.ncbi.nlm.nih.gov/pubmed/18365023 http://dx.doi.org/10.1371/journal.pone.0001882 |