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Notch Signaling Regulates Bile Duct Morphogenesis in Mice
BACKGROUND: Alagille syndrome is a developmental disorder caused predominantly by mutations in the Jagged1 (JAG1) gene, which encodes a ligand for Notch family receptors. A characteristic feature of Alagille syndrome is intrahepatic bile duct paucity. We described previously that mice doubly heteroz...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266994/ https://www.ncbi.nlm.nih.gov/pubmed/18365007 http://dx.doi.org/10.1371/journal.pone.0001851 |