Nickel(II), Copper(II) and Zinc(II) Complexes of 9-[2- (Phosphonomethoxy)ethyl]-8-azaadenine (9,8aPMEA), the 8-Aza Derivative of the Antiviral Nucleotide Analogue 9-[2-(Phosphonomethoxy)ethyl] adenine (PMEA). Quantification of Four Isomeric Species in Aqueous Solution

The acidity constants of the twofold protonated acyclic nucleotide analogue 9-[2-(phosphonomethoxy)- ethyl]-8-azaadenine, H(2)(9,8aPMEA)(±), as well as the stability constants of the M(H;9,8aPMEA)(+) and M(9,8aPMEA) complexes with the metal ions M(2+) =Ni(2+), Cu(2+) or Zn(2+), have been determined...

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Detalles Bibliográficos
Autores principales: Gómez-Coca, Raquel B., Holý, Antonín, Vilaplana, Rosario A., González-Vílchez, Francisco, Sigel, Helmut
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267076/
https://www.ncbi.nlm.nih.gov/pubmed/18365084
http://dx.doi.org/10.1155/S1565363304000202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267076/
https://www.ncbi.nlm.nih.gov/pubmed/18365084
http://dx.doi.org/10.1155/S1565363304000202

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