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Nickel(II), Copper(II) and Zinc(II) Complexes of 9-[2- (Phosphonomethoxy)ethyl]-8-azaadenine (9,8aPMEA), the 8-Aza Derivative of the Antiviral Nucleotide Analogue 9-[2-(Phosphonomethoxy)ethyl] adenine (PMEA). Quantification of Four Isomeric Species in Aqueous Solution
The acidity constants of the twofold protonated acyclic nucleotide analogue 9-[2-(phosphonomethoxy)- ethyl]-8-azaadenine, H(2)(9,8aPMEA)(±), as well as the stability constants of the M(H;9,8aPMEA)(+) and M(9,8aPMEA) complexes with the metal ions M(2+) =Ni(2+), Cu(2+) or Zn(2+), have been determined...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267076/ https://www.ncbi.nlm.nih.gov/pubmed/18365084 http://dx.doi.org/10.1155/S1565363304000202 |