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Synthesis and in vitro Antitumor Potency of (Cyclohexane-1,2-Diamine)Platinum(II) Complexes with Aminotris(Methylenephosphonic Acid) as Bone-Seeking Ligand

In order to develop platinum complexes with selective activity in primary and secondary bone malignancies and with the aim to optimize antitumor activity, platinum(II) complexes with aminotris(methylenephosphonic acid) as bone-seeking (osteotropic) ligand have been synthesized, characterized and tes...

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Detalles Bibliográficos
Autores principales: Galanski, Markus, Slaby, Susanna, Jakupec, Michael A., Keppler, Bernhard K.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267107/
https://www.ncbi.nlm.nih.gov/pubmed/18365098
http://dx.doi.org/10.1155/BCA.2005.179