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Competition between Delta and the Abruptex domain of Notch
BACKGROUND: Extracellular domains of the Notch family of signalling receptors contain many EGF repeat domains, as do their major ligands. Some EGF repeats are modified by O-fucosylation, and most have no identified role in ligand binding. RESULTS: Using a binding assay with purified proteins in vitr...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267168/ https://www.ncbi.nlm.nih.gov/pubmed/18208612 http://dx.doi.org/10.1186/1471-213X-8-4 |