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Multilayered epithelium in a rat model and human Barrett's esophagus: Similar expression patterns of transcription factors and differentiation markers

BACKGROUND: In rats, esophagogastroduodenal anastomosis (EGDA) without concomitant chemical carcinogen treatment leads to gastroesophageal reflux disease, multilayered epithelium (MLE, a presumed precursor in intestinal metaplasia), columnar-lined esophagus, dysplasia, and esophageal adenocarcinoma....

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Detalles Bibliográficos
Autores principales: Chen, Xiaoxin, Qin, Rong, Liu, Ba, Ma, Yan, Su, Yinghao, Yang, Chung S, Glickman, Jonathan N, Odze, Robert D, Shaheen, Nicholas J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267197/
https://www.ncbi.nlm.nih.gov/pubmed/18190713
http://dx.doi.org/10.1186/1471-230X-8-1