Haplotype Reconstruction Error as a Classical Misclassification Problem: Introducing Sensitivity and Specificity as Error Measures

BACKGROUND: Statistically reconstructing haplotypes from single nucleotide polymorphism (SNP) genotypes, can lead to falsely classified haplotypes. This can be an issue when interpreting haplotype association results or when selecting subjects with certain haplotypes for subsequent functional studie...

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Detalles Bibliográficos
Autores principales: Lamina, Claudia, Bongardt, Friedhelm, Küchenhoff, Helmut, Heid, Iris M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267219/
https://www.ncbi.nlm.nih.gov/pubmed/18365008
http://dx.doi.org/10.1371/journal.pone.0001853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267219/
https://www.ncbi.nlm.nih.gov/pubmed/18365008
http://dx.doi.org/10.1371/journal.pone.0001853

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