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A DNA vaccine against tuberculosis based on the 65 kDa heat-shock protein differentially activates human macrophages and dendritic cells

BACKGROUND: A number of reports have demonstrated that rodents immunized with DNA vaccines can produce antibodies and cellular immune responses presenting a long-lasting protective immunity. These findings have attracted considerable interest in the field of DNA vaccination. We have previously descr...

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Detalles Bibliográficos
Autores principales: Franco, Luís H, Wowk, Pryscilla F, Silva, Célio L, Trombone, Ana PF, Coelho-Castelo, Arlete AM, Oliver, Constance, Jamur, Maria C, Moretto, Edson L, Bonato, Vânia LD
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267464/
https://www.ncbi.nlm.nih.gov/pubmed/18208592
http://dx.doi.org/10.1186/1479-0556-6-3