Cargando…
A DNA vaccine against tuberculosis based on the 65 kDa heat-shock protein differentially activates human macrophages and dendritic cells
BACKGROUND: A number of reports have demonstrated that rodents immunized with DNA vaccines can produce antibodies and cellular immune responses presenting a long-lasting protective immunity. These findings have attracted considerable interest in the field of DNA vaccination. We have previously descr...
Autores principales: | Franco, Luís H, Wowk, Pryscilla F, Silva, Célio L, Trombone, Ana PF, Coelho-Castelo, Arlete AM, Oliver, Constance, Jamur, Maria C, Moretto, Edson L, Bonato, Vânia LD |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267464/ https://www.ncbi.nlm.nih.gov/pubmed/18208592 http://dx.doi.org/10.1186/1479-0556-6-3 |
Ejemplares similares
-
Tissue distribution of DNA-Hsp65/TDM-loaded PLGA microspheres and uptake by phagocytic cells
por: Trombone, Ana Paula F, et al.
Publicado: (2007) -
Endocytosis of DNA-Hsp65 Alters the pH of the Late Endosome/Lysosome and Interferes with Antigen Presentation
por: Trombone, Ana Paula F., et al.
Publicado: (2007) -
DNA vaccine containing the mycobacterial hsp65 gene prevented insulitis in MLD-STZ diabetes
por: Santos, Rubens R, et al.
Publicado: (2009) -
Detrimental Effect of Fungal 60-kDa Heat Shock Protein on Experimental Paracoccidioides brasiliensis Infection
por: Fernandes, Fabrício Freitas, et al.
Publicado: (2016) -
Genetic vaccine for tuberculosis (pVAXhsp65) primes neonate mice for a strong immune response at the adult stage
por: Pelizon, Ana Cláudia, et al.
Publicado: (2007)