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Clostridial spores as live 'Trojan horse' vectors for cancer gene therapy: comparison with viral delivery systems

Solid tumours account for 90% of all cancers. Gene therapy represents a potential new modality for their treatment. Up to now, several approaches have been developed, but the most efficient ones are the viral vector based gene therapy systems. However, viral vectors suffer from several deficiencies:...

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Detalles Bibliográficos
Autores principales: Wei, Ming Q, Ren, Ruimei, Good, David, Anné, Jozef
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267465/
https://www.ncbi.nlm.nih.gov/pubmed/18279524
http://dx.doi.org/10.1186/1479-0556-6-8