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Clostridial spores as live 'Trojan horse' vectors for cancer gene therapy: comparison with viral delivery systems
Solid tumours account for 90% of all cancers. Gene therapy represents a potential new modality for their treatment. Up to now, several approaches have been developed, but the most efficient ones are the viral vector based gene therapy systems. However, viral vectors suffer from several deficiencies:...
Autores principales: | Wei, Ming Q, Ren, Ruimei, Good, David, Anné, Jozef |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267465/ https://www.ncbi.nlm.nih.gov/pubmed/18279524 http://dx.doi.org/10.1186/1479-0556-6-8 |
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