Formation of amyloid fibrils in vitro by human γD-crystallin and its isolated domains

PURPOSE: Amyloid fibrils are associated with a variety of human protein misfolding and protein deposition diseases. Previous studies have shown that bovine crystallins form amyloid fibers under denaturing conditions and amyloid fibers accumulate in the lens of mice carrying mutations in crystallin g...

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Detalles Bibliográficos
Autores principales: Papanikolopoulou, Katerina, Mills-Henry, Ishara, Thol, Shannon L., Wang, Yongting, Gross, Abby A.R., Kirschner, Daniel A., Decatur, Sean M., King, Jonathan
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267726/
https://www.ncbi.nlm.nih.gov/pubmed/18253099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267726/
https://www.ncbi.nlm.nih.gov/pubmed/18253099

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