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A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas

The computational identification of oncogenic lesions is still a key open problem in cancer biology. Although several methods have been proposed, they fail to model how such events are mediated by the network of molecular interactions in the cell. In this paper, we introduce a systems biology approa...

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Detalles Bibliográficos
Autores principales: Mani, Kartik M, Lefebvre, Celine, Wang, Kai, Lim, Wei Keat, Basso, Katia, Dalla-Favera, Riccardo, Califano, Andrea
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267731/
https://www.ncbi.nlm.nih.gov/pubmed/18277385
http://dx.doi.org/10.1038/msb.2008.2