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A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas
The computational identification of oncogenic lesions is still a key open problem in cancer biology. Although several methods have been proposed, they fail to model how such events are mediated by the network of molecular interactions in the cell. In this paper, we introduce a systems biology approa...
Autores principales: | Mani, Kartik M, Lefebvre, Celine, Wang, Kai, Lim, Wei Keat, Basso, Katia, Dalla-Favera, Riccardo, Califano, Andrea |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267731/ https://www.ncbi.nlm.nih.gov/pubmed/18277385 http://dx.doi.org/10.1038/msb.2008.2 |
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