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Accurate prediction of protein–protein interactions from sequence alignments using a Bayesian method
Accurate and large-scale prediction of protein–protein interactions directly from amino-acid sequences is one of the great challenges in computational biology. Here we present a new Bayesian network method that predicts interaction partners using only multiple alignments of amino-acid sequences of i...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267735/ https://www.ncbi.nlm.nih.gov/pubmed/18277381 http://dx.doi.org/10.1038/msb4100203 |