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Prediction of Human Disease Genes by Human-Mouse Conserved Coexpression Analysis

BACKGROUND: Even in the post-genomic era, the identification of candidate genes within loci associated with human genetic diseases is a very demanding task, because the critical region may typically contain hundreds of positional candidates. Since genes implicated in similar phenotypes tend to share...

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Detalles Bibliográficos
Autores principales: Ala, Ugo, Piro, Rosario Michael, Grassi, Elena, Damasco, Christian, Silengo, Lorenzo, Oti, Martin, Provero, Paolo, Di Cunto, Ferdinando
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268251/
https://www.ncbi.nlm.nih.gov/pubmed/18369433
http://dx.doi.org/10.1371/journal.pcbi.1000043