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Aberrant epigenetic changes and gene expression in cloned cattle dying around birth

BACKGROUND: Aberrant reprogramming of donor somatic cell nuclei may result in many severe problems in animal cloning. To assess the extent of abnormal epigenetic modifications and gene expression in clones, we simultaneously examined DNA methylation, histone H4 acetylation and expression of six gene...

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Detalles Bibliográficos
Autores principales: Lin, Li, Li, Qiang, Zhang, Lei, Zhao, Dingsheng, Dai, Yunping, Li, Ning
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268668/
https://www.ncbi.nlm.nih.gov/pubmed/18261243
http://dx.doi.org/10.1186/1471-213X-8-14