Forced expression of the cell cycle inhibitor p57(Kip2 )in cardiomyocytes attenuates ischemia-reperfusion injury in the mouse heart

BACKGROUND: Myocardial hypoxic-ischemic injury is the cause of significant morbidity and mortality worldwide. The cardiomyocyte response to hypoxic-ischemic injury is known to include changes in cell cycle regulators. The cyclin-dependent kinase inhibitor p57(Kip2 )is involved in cell cycle control,...

Descripción completa

Detalles Bibliográficos
Autores principales: Haley, Sheila A, Zhao, Ting, Zou, Lijun, Klysik, Jan E, Padbury, James F, Kochilas, Lazaros K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268709/
https://www.ncbi.nlm.nih.gov/pubmed/18312674
http://dx.doi.org/10.1186/1472-6793-8-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268709/
https://www.ncbi.nlm.nih.gov/pubmed/18312674
http://dx.doi.org/10.1186/1472-6793-8-4

Ejemplares similares