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Quantification of PRL/Stat5 signaling with a novel pGL4-CISH reporter

BACKGROUND: Elevations of serum prolactin (PRL) are associated with an increased risk for breast cancer. PRL signaling through its prolactin receptor (PRLr) involves the Jak2/Stat5 pathway. Luciferase-based reporter assays have been widely used to evaluate the activity of this pathway. However, the...

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Detalles Bibliográficos
Autores principales: Fang, Feng, Antico, Giovanni, Zheng, Jiamao, Clevenger, Charles V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268924/
https://www.ncbi.nlm.nih.gov/pubmed/18254957
http://dx.doi.org/10.1186/1472-6750-8-11