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Quantification of PRL/Stat5 signaling with a novel pGL4-CISH reporter
BACKGROUND: Elevations of serum prolactin (PRL) are associated with an increased risk for breast cancer. PRL signaling through its prolactin receptor (PRLr) involves the Jak2/Stat5 pathway. Luciferase-based reporter assays have been widely used to evaluate the activity of this pathway. However, the...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268924/ https://www.ncbi.nlm.nih.gov/pubmed/18254957 http://dx.doi.org/10.1186/1472-6750-8-11 |