Inhibition of oncogene-induced inflammatory chemokines using a farnesyltransferase inhibitor

BACKGROUND: Farnesyltransferase inhibitors (FTI) are small molecule agents originally formulated to inhibit the oncogenic functions of Ras. Although subsequent analysis of FTI activity revealed wider effects on other pathways, the drug has been demonstrated to reduce Ras signaling by direct measurem...

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Detalles Bibliográficos
Autores principales: DeGeorge, Katharine C, DeGeorge, Brent R, Testa, James S, Rothstein, Jay L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268934/
https://www.ncbi.nlm.nih.gov/pubmed/18304343
http://dx.doi.org/10.1186/1476-9255-5-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268934/
https://www.ncbi.nlm.nih.gov/pubmed/18304343
http://dx.doi.org/10.1186/1476-9255-5-3

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