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Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: A systematic expression analysis

BACKGROUND: The inter-alpha-trypsin inhibitors (ITI) are a family of plasma protease inhibitors, assembled from a light chain – bikunin, encoded by AMBP – and five homologous heavy chains (encoded by ITIH1, ITIH2, ITIH3, ITIH4, and ITIH5), contributing to extracellular matrix stability by covalent l...

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Detalles Bibliográficos
Autores principales: Hamm, Alexander, Veeck, Juergen, Bektas, Nuran, Wild, Peter J, Hartmann, Arndt, Heindrichs, Uwe, Kristiansen, Glen, Werbowetski-Ogilvie, Tamra, Del Maestro, Rolando, Knuechel, Ruth, Dahl, Edgar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268946/
https://www.ncbi.nlm.nih.gov/pubmed/18226209
http://dx.doi.org/10.1186/1471-2407-8-25