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SpvC is a Salmonella effector with phosphothreonine lyase activity on host mitogen-activated protein kinases

SpvC is encoded by the Salmonella virulence plasmid. We have investigated the biochemical function of SpvC and the mechanism by which it is secreted by bacteria and translocated into infected macrophages. We constructed a strain carrying a deletion in spvC and showed that the strain is attenuated fo...

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Detalles Bibliográficos
Autores principales: Mazurkiewicz, Piotr, Thomas, Jerry, Thompson, Jessica A, Liu, Mei, Arbibe, Laurence, Sansonetti, Philippe, Holden, David W
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268955/
https://www.ncbi.nlm.nih.gov/pubmed/18284579
http://dx.doi.org/10.1111/j.1365-2958.2008.06134.x