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SpvC is a Salmonella effector with phosphothreonine lyase activity on host mitogen-activated protein kinases
SpvC is encoded by the Salmonella virulence plasmid. We have investigated the biochemical function of SpvC and the mechanism by which it is secreted by bacteria and translocated into infected macrophages. We constructed a strain carrying a deletion in spvC and showed that the strain is attenuated fo...
Autores principales: | Mazurkiewicz, Piotr, Thomas, Jerry, Thompson, Jessica A, Liu, Mei, Arbibe, Laurence, Sansonetti, Philippe, Holden, David W |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268955/ https://www.ncbi.nlm.nih.gov/pubmed/18284579 http://dx.doi.org/10.1111/j.1365-2958.2008.06134.x |
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