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Role of Metal Ions and Hydrogen Bond Acceptors in the Tautomeric Equilibrium of Nitro-9[(Alkylamino)Amino]-Acridine Drugs

3-nitro-9-[2-(dialkylamino)ethyl)]aminoacridines (alkyl = methyl or ethyl) have been used as ligands towards platinum(If). The end product is a complex in which the acridine acts as a tridentate ligand contributing the two exocyclic nitrogen atoms and one of the two peri carbons. The metallation tak...

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Detalles Bibliográficos
Autores principales: Carlone, Maria, Di Masi, Nicola G., Maresca, Luciana, Margiotta, Nicola, Natile, Giovanni
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2269723/
https://www.ncbi.nlm.nih.gov/pubmed/18365071
http://dx.doi.org/10.1155/S156536330400007X