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Neuronal pentraxin II is highly upregulated in Parkinson’s disease and a novel component of Lewy bodies

Neuronal pentraxin II (NPTX2) is the most highly upregulated gene in the Parkinsonian substantia nigra based on our whole genome expression profiling results. We show here that it is a novel component of Lewy bodies and Lewy neurites in sporadic Parkinson’s disease (PD). NPTX2 is also known as the n...

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Detalles Bibliográficos
Autores principales: Moran, Linda B., Hickey, Lorraine, Michael, Gregory J., Derkacs, Maria, Christian, Lynne M., Kalaitzakis, Michail E., Pearce, Ronald K. B., Graeber, Manuel B.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270353/
https://www.ncbi.nlm.nih.gov/pubmed/17987278
http://dx.doi.org/10.1007/s00401-007-0309-3