Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes

BACKGROUND/HYPOTHESIS: HLA, INS, PTPN22 and CTLA4 are considered to be confirmed type 1 diabetes susceptibility genes. HLA, PTPN22 and CTLA4 are known to be involved in immune regulation. Few studies have systematically investigated the joint effect of multiple genetic variants. We evaluated joint e...

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Detalles Bibliográficos
Autores principales: Bjørnvold, M., Undlien, D. E., Joner, G., Dahl-Jørgensen, K., Njølstad, P. R., Akselsen, H. E., Gervin, K., Rønningen, K. S., Stene, L. C.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270365/
https://www.ncbi.nlm.nih.gov/pubmed/18292987
http://dx.doi.org/10.1007/s00125-008-0932-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270365/
https://www.ncbi.nlm.nih.gov/pubmed/18292987
http://dx.doi.org/10.1007/s00125-008-0932-0

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