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Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes
BACKGROUND/HYPOTHESIS: HLA, INS, PTPN22 and CTLA4 are considered to be confirmed type 1 diabetes susceptibility genes. HLA, PTPN22 and CTLA4 are known to be involved in immune regulation. Few studies have systematically investigated the joint effect of multiple genetic variants. We evaluated joint e...
Autores principales: | Bjørnvold, M., Undlien, D. E., Joner, G., Dahl-Jørgensen, K., Njølstad, P. R., Akselsen, H. E., Gervin, K., Rønningen, K. S., Stene, L. C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270365/ https://www.ncbi.nlm.nih.gov/pubmed/18292987 http://dx.doi.org/10.1007/s00125-008-0932-0 |
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