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Cisplatin-DNA adduct formation in patients treated with cisplatin-based chemoradiation: lack of correlation between normal tissues and primary tumor

PURPOSE: In this study, the formation of cisplatin-DNA adducts after concurrent cisplatin-radiation and the relationship between adduct-formation in primary tumor tissue and normal tissue were investigated. METHODS: Three intravenous cisplatin-regimens, given concurrently with radiation, were studie...

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Detalles Bibliográficos
Autores principales: Hoebers, F. J. P., Pluim, D., Hart, A. A. M., Verheij, M., Balm, A. J. M., Fons, G., Rasch, C. R. N., Schellens, J. H. M., Stalpers, L. J. A., Bartelink, H., Begg, A. C.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270367/
https://www.ncbi.nlm.nih.gov/pubmed/17639394
http://dx.doi.org/10.1007/s00280-007-0545-1