Antigen Presenting Cells and Stromal Cells Trigger Human Natural Killer Lymphocytes to Autoreactivity: Evidence for the Involvement of Natural Cytotoxicity Receptors (NCR) and NKG2D

Human natural killer (NK) lymphocytes should not damage autologous cells due to the engagement of inhibitory receptor superfamily (IRS) members by HLA-I. Nevertheless, NK cells kill self cells expressing low levels or lacking HLA-I, as it may occur during viral infections (missing-self hypothesis)....

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Detalles Bibliográficos
Autores principales: Poggi, Alessandro, Zocchi, Maria Raffaella
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270773/
https://www.ncbi.nlm.nih.gov/pubmed/17162374
http://dx.doi.org/10.1080/17402520600578194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270773/
https://www.ncbi.nlm.nih.gov/pubmed/17162374
http://dx.doi.org/10.1080/17402520600578194

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