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Pathogenesis of cerebral malformations in human fetuses with meningomyelocele

BACKGROUND: Fetal spina bifida aperta (SBA) is characterized by a spinal meningomyelocele (MMC) and associated with cerebral pathology, such as hydrocephalus and Chiari II malformation. In various animal models, it has been suggested that a loss of ventricular lining (neuroepithelial/ependymal denud...

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Detalles Bibliográficos
Autores principales: de Wit, Olga A, den Dunnen, Wilfred FA, Sollie, Krystyne M, Muñoz, Rosa Iris, Meiners, Linda C, Brouwer, Oebele F, Rodríguez, Esteban M, Sival, Deborah A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270798/
https://www.ncbi.nlm.nih.gov/pubmed/18312688
http://dx.doi.org/10.1186/1743-8454-5-4