Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKA(y )mice

BACKGROUND: A substantial body of evidence indicates that reduced plasma adiponectin levels may be key in the development of insulin resistance, type 2 diabetes and the metabolic syndrome. Glucocorticoids decrease the levels of adiponectin in animals and humans. Cortisone is transformed to its activ...

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Detalles Bibliográficos
Autores principales: Sundbom, Maj, Kaiser, Christina, Björkstrand, Eva, Castro, Victor M, Larsson, Catarina, Selén, Göran, Nyhem, Charlotte Söderberg, James, Stephen R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270815/
https://www.ncbi.nlm.nih.gov/pubmed/18269730
http://dx.doi.org/10.1186/1471-2210-8-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270815/
https://www.ncbi.nlm.nih.gov/pubmed/18269730
http://dx.doi.org/10.1186/1471-2210-8-3

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