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Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKA(y )mice

BACKGROUND: A substantial body of evidence indicates that reduced plasma adiponectin levels may be key in the development of insulin resistance, type 2 diabetes and the metabolic syndrome. Glucocorticoids decrease the levels of adiponectin in animals and humans. Cortisone is transformed to its activ...

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Detalles Bibliográficos
Autores principales:	Sundbom, Maj, Kaiser, Christina, Björkstrand, Eva, Castro, Victor M, Larsson, Catarina, Selén, Göran, Nyhem, Charlotte Söderberg, James, Stephen R
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270815/ https://www.ncbi.nlm.nih.gov/pubmed/18269730 http://dx.doi.org/10.1186/1471-2210-8-3

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